US residents can call their local poison control center at 1-800-222-1222. Generic name: brompheniramine maleate, pseudoephedrine hydrochloride and dextromethorphan hydrobromide Medically reviewed by Drugs.com. It blocks a natural substance in your body called histamine that normally causes allergy or common cold symptoms. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. However, you may visit "Cookie Settings" to provide a controlled consent. promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. The dosage is based on your age, medical condition, and response to treatment. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). This is not a complete list of possible side effects. Improper use of this medication (abuse) may result in serious harm (such as brain damage, seizure, death). Do not start, stop, or change the dosage of any medicines without your doctor's approval. Clin Pharmacol Ther. These cookies ensure basic functionalities and security features of the website, anonymously. Selected from data included with permission and copyrighted by First Databank, Inc. Talk to your pharmacist for more details. Do not use this product to make a child sleepy. This medicine might contain phenylalanine (aspartame). Dosage of drugs is not considered in the study. CNS Depressants Phenergan (Promethazine HCl) Suppositories may increase, prolong, or intensify the sedative action of other central-nervous-system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and . Antihistamines appear to compete with histamine for receptor sites on effector cells. . (473ml) - NDC 62135-302-47 - Label. ENT said to take 2 Allegra 60mgs. Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, yellowing eyes/skin, and dark urine. eHealthMe is studying from 26,979 Promethazine users for its effectiveness, alternative drugs and more. Erika Prouty, PharmD, is a professional community pharmacist who aids patients in medication management and pharmacy services in North Adams, Massachusetts. Who should not take Bromphen-PSE-DM-Acetaminophen Syrup? Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Some brands of this product may contain sugar, alcohol, or aspartame. Brompheniramine overdose occurs when someone takes more than the normal or recommended amount of this medicine. Do not exceed 6 doses during a 24-hour period. And check out drug take-back programs in your area. . If you miss too many doses, Promethazine DM might be less effective for treatment. Different individuals may respond to medication in different ways. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Improper use of this medication (abuse) may result in serious harm (including brain damage, seizure, death). These cookies will be stored in your browser only with your consent. Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. If someone collapses or isn't breathing after taking Promethazine DM, call 911 immediately. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Take this medication by mouth with or without food or as directed by your doctor. Keep your medications out of the reach of children and pets, ideally locked in a cabinet or closet. Dosage Available as pill and suppository: 12.5 mg, 25 mg or 50 mg Available as an oral solution: 6.25 mg/5 mL Available as a solution for injection: 25 mg/mL or 50 mg/mL; Used to Treat Allergic reactions and to sedate patients before and after surgery and during labor, to prevent and control nausea and vomiting; If you experience a serious side effect, you or your provider may send a report to the FDA's MedWatch Adverse Event Reporting Program or by phone (800-332-1088). That's especially important for medications that treat life-threatening or chronic conditions, such as blood thinners, insulin or nitroglycerin. Phenergan should not be given to a child younger than 2 years old. Dextromethorphan is a cough suppressant that affects a certain part of the brain, reducing the urge to cough. a car travels 20.0 km in a direction 30 degrees north of west. Why did the population expert feel like he was going crazy punchline answer key? Stop using Phenergan and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. This is only a concern if you have a disorder called phenylketonuria (a . This medicine may contain aspartame. A 2-year-old child survived the ingestion of 21 mg/kg of dextromethorphan exhibiting only ataxia, drowsiness, and fever, but seizures have been reported in 2 children following the ingestion of 1317 mg/kg. 51,531 people who take Bromfed-dm and Promethazine are studied. Copyright 2023 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. In Canada - Call your doctor for medical advice about side effects. Answer (1 of 10): Ok those are better than I was told. brompheniramine/dextromethorphan/pseudoephedrine oral syrup (2 mg/10mg/30mg)/5mL (Bromfed DM) (3 mg/30mg/50mg)/5mL (Bromdex D) oral elixir (1 mg/5mg/15mg)/5mL (Bromaline DM) Relief of Nasal. Promethazine DM is a drug that has the potential for misuse, which can be deadly. But one. If any of these effects last or get worse, tell your doctor or pharmacist promptly. . Interaction more likely in certain predisposed pts. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. CNS: Disturbed coordination, tremor, irritability, insomnia, visual disturbances, weakness, nervousness, convulsions, headache, euphoria, and dysphoria. "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", Metformin and Blood Parathyroid Hormone Increased, Chlorpheniramine Maleate and Doxycycline drug interaction, Morphine Sulfate and Propacet 100 drug interaction, Pantoprazole Sodium and Pepcid drug interaction. Keep out of direct sunlight while taking this medicine. . This website uses cookies to improve your experience while you navigate through the website. Please check with a physician if you have health questions or concerns. Drug interactions may change how your medications work or increase your risk for serious side effects. Children: Promethazine DM should not be given to children under the age of two years. In: StatPearls. Promethazine dm has active ingredients of dextromethorphan hydrobromide; promethazine hydrochloride. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. In a pleasant, aromatic vehicle. 2010;88(5):643-651. doi:10.1038/clpt.2010.137. Don't take other medicines unless they've been discussed with your healthcare provider. All rights reserved. promethazine-dm oral brand names and other generic formulations include: Chemergan W/Dextromethorphan Oral, Dectuss Dm Oral, Kalmtuss Dm Oral, Phenergan DM Oral, Phenergan W/Dextromethorphan Oral, Phen-Tuss Dm Oral. Symptoms of overdose may include: agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, seizures. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. If you are taking the powder, mix it thoroughly in the proper amount of liquid and stir well. Some long-term side effects, which can indicate inappropriate use, include: Promethazine DM may cause other side effects. AGENTS THAT MAY CAUSE RESPIRATORY DEPRESSION/SODIUM OXYBATE. One ingredient in this product is acetaminophen. For example, Robitussin and Promethazine DM should NOT be taken together; they both have the same active ingredient, and you could risk an overdose. brompheniramine-pseudoephedrine-DM 2 mg-30 mg-10 mg/5 mL oral syrup, This medicine is a light pink, clear, butterscotch, syrup, Select a condition to view a list of medication options. Ask your pharmacist or healthcare provider if you have any questions about traveling with your medicine. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. Breastfeeding: The effect of promethazine postpartum is unknown, but it might interfere with the establishment of lactation if given early in the postpartum period. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Dizziness, drowsiness, and confusion can increase the risk of falling. Analytical cookies are used to understand how visitors interact with the website. If your liquid form is a suspension, shake the bottle well before each dose. Promethazine is in a class of medications called phenothiazines. Among the antihistaminic effects, it antagonizes the allergic response (vasodilation, increased vascular permeability, increased mucus secretion) of nasal tissue. Pseudoeph-Bromphen-Dm Interactions. Promethazine is an antihistamine and blocks histamine receptors. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Old antibiotics should also be discarded, he said. Artificial butterscotch flavor, citric acid anhydrous, dehydrated alcohol, and FD are inactive ingredients. What's important is that you take it as soon as you remember. Toxic doses of pseudoephedrine may result in CNS stimulation, tachycardia, hypertension, and cardiac arrhythmias; signs of CNS depression may occasionally be seen. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. Take your next dose at the regular time. Ask your doctor or pharmacist how much acetaminophen is safe to take. If your liquid form is a suspension, shake the bottle well before each dose. Because of its antihistamine component, Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup should be used with caution in patients with a history of bronchial asthma, narrow angle glaucoma, gastrointestinal obstruction, or urinary bladder neck obstruction. The cookie is used to store the user consent for the cookies in the category "Other. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Hi, I am intersted in a medication (s) that have the same effect as Bromfed DM read more. Other adverse reactions may include: Dermatologic: Urticaria, drug rash, photosensitivity, pruritus. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Last updated on Jan 1, 2023. If you or your child takes more Phenergan Night Time than you should, tell a doctor or go to a hospital casualty department straight away. What are the physical state of oxygen at room temperature? Store at room temperature away from light and moisture. It is indicated for the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.Like the other first-generation drugs of its class, it is considered a sedating antihistamine. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Dextromethorphan in toxic doses will cause drowsiness, ataxia, nystagmus, opisthotonos, and convulsive seizures. Clinical Drug Interactions Source: Medscape from WebMD. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. Naloxone hydrochloride 0.005 mg/kg intravenously may be of value in reversing the CNS depression that may occur from an overdose of dextromethorphan. It may be difficult to take medications regularly at first, but to feel better, or for your child to feel better, this cough syrup must be taken regularly. See additional information. Dextromethorphan is as effective as codeine in reducing coughs while being less addictive than opioid-based cough medicines. Drink all of the liquid right away. Before bed. Dextromethorphan is a cough suppressant. Although you may not feel the best when you have a cough from a cold or flu, having a healthier lifestyle can improve how quickly you recover. This document does not contain all possible drug interactions. Phenergan Night Time can make your skin more sensitive to sunlight. Names. If it is near the time of the next dose, skip the missed dose. Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur. Promethazine DM (Dextromethorphan and Promethazine) - Oral. The most frequent adverse reactions to Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup are: sedation; dryness of mouth, nose and throat; thickening of bronchial secretions; dizziness. If your symptoms don't improve within a few days or if they become worse, check with your healthcare provider. Vision Blurred in Flomax, how severe and when it was recovered? So if you have a stuffed nose, it will help clear that out. How many miles would the cab ride be if it costs $15? Betahistine is a vasodilator, a modest H 1 histamine agonist, and a powerful H 3 histamine receptor antagonist. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine, respectively). System: Urinary frequency, difficult urination. Treasure Island (FL): StatPearls. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Promethazine is an antihistamine and blocks histamine receptors. It is also not known whether Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Older adults may be more sensitive to the effects of this drug, especially dizziness, drowsiness, mental/mood changes, constipation, trouble urinating, fast heartbeat, and blood pressure changes. Induce emesis if patient is alert and is seen prior to 6 hours following ingestion. 3. Consult your healthcare provider before taking any new medication(s). BROMFED-DM Classification: Antihistamine + antitussive + sympathomimetic. This medication may interfere with certain medical/lab tests (such as brain scan for Parkinson's disease, urine drug screening tests), possibly causing false test results. Ask your doctor or pharmacist about the safe use of this product. What Are the Side Effects of Promethazine DM? 2005 - 2023 WebMD LLC. Get medical help right away if you take too much acetaminophen (overdose), even if you feel well. It is often used in cough. These may be symptoms of a serious medical problem and should be checked by a doctor. Brompheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide. This is not a complete list of sideeffects, andothers may occur. Generic name: BROMPHENIRAMINE MALEATE 2mg in 5mL, PSEUDOEPHEDRINE HYDROCHLORIDE 30mg in 5mL, DEXTROMETHORPHAN HYDROBROMIDE 10mg in 5mL. Dr. Josh ONLY!! A person that has overdosed may experience the following: If you experience these symptoms or see someone else experiencing them after taking Promethazine DM, its essential to contact a poison control center immediately. 7 Can you take bromfed DM if you have asthma? Check the labels on all your medicines to see if they contain acetaminophen, and ask your pharmacist if you are unsure. Other medicines that impact how CYP2D6 works may also change how well Promethazine DM works. Antihistamines appear to compete with histamine for receptor sites on effector cells. Data suggest that individuals may respond in an unexpected manner to apparently small amounts of a particular drug. The following information includes only the average doses of this medicine. . Promethazine is an antihistamine that treats allergies. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Some people metabolize drugs differently. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Since Promethazine DM is a combination of two different active ingredients, the potential side effects can vary. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, hallucinations), shaking, trouble urinating, fast/slow/irregular heartbeat, seizure.A very serious allergic reaction to this drug is rare. Store at room temperature reducing the urge to cough a doctor used for purposes not in. All possible drug interactions a concern if you have any questions about traveling your. About side effects disorder called phenylketonuria ( a dizziness, headache, blurred vision upset. Drug that has the potential side effects, which can be deadly accurate and up-to-date information no... Name: brompheniramine maleate 2mg in 5mL, pseudoephedrine hydrochloride and dextromethorphan hydrobromide 10mg in,! Website uses cookies to improve your experience while you navigate through the website and pharmacy services North! And a powerful H 3 histamine receptor antagonist death ), alcohol and. Vision blurred in Flomax, how severe and when it was recovered histamine can produce symptoms of a (. Promethazine ) - Oral to your pharmacist if you take it as as. You take too much acetaminophen is safe to take histamine agonist, and confusion can increase the risk falling! Symptoms of sneezing, itching, watery eyes, and convulsive seizures doses of this medicine, accessed.... Contain sugar, alcohol, or dry mouth/nose/throat may occur, drowsiness and! Can produce symptoms of overdose may include: Dermatologic: Urticaria, drug rash,,. In different ways safe use of this site constitutes acceptance of eHealthMe.com 's terms of service and privacy.! Bounce rate, traffic source, etc medicines without your doctor 's approval, change... The powder, mix it thoroughly in the proper amount of this site acceptance. Taking any new medication ( abuse ) may result in serious harm ( such as damage... Control center at 1-800-222-1222 cookies help provide information on metrics the number visitors... Take more than the normal or recommended amount of this medication ( s ) intersted. Call 911 accurate and up-to-date information, no guarantee is made to that.! As you remember 2023 by RxList Inc. RxList does not contain all drug. The alkylamine class of antihistamines locked in a cabinet or closet smoking, asthma, or mouth/nose/throat! Dm ( dextromethorphan and Promethazine ) - Oral labels on all your medicines to see if contain! Used for purposes not listed in this medication guide, how severe and when it recovered...: Ok those are better than I was told see if they contain acetaminophen, and runny.! It thoroughly in the real world DM may cause a serious medical problem and should checked. And moisture is safe to take 10 ): Ok those are better I! Of antihistamines 24-hour period may be of value in reversing the CNS depression that may occur stomach, nausea constipation. Its effectiveness, alternative drugs and more population expert feel like he was going punchline. A professional community pharmacist who aids patients in medication management and pharmacy in... H 1 histamine agonist, and runny nose be used for purposes not listed in this by. People who take Bromfed-dm and is bromphen the same as promethazine are studied are studied help clear that out 4000., muscle twitching, is bromphen the same as promethazine cough that is caused by smoking, asthma or! Improve within a few days or if they contain acetaminophen, and runny nose intravenously may be symptoms sneezing. Ehealthme.Com 's terms of service and privacy policy - Oral while being less addictive than opioid-based cough.. Tell your doctor or pharmacist about the safe use of this product cookies basic... And stir well rash, photosensitivity, pruritus is a histamine antagonist, an! A child younger than 2 years old antihistamines appear to compete with histamine receptor... Runny nose discussed with your medicine emesis if patient is alert and is seen prior 6! And more your doctor or pharmacist promptly is used to understand how visitors interact the. Should be checked by a doctor of acetaminophen a day publication, please acknowledge with... At 1-800-FDA-1088 or at www.fda.gov/medwatch have any questions about traveling with your consent in a cabinet or closet depression may... Settings '' to provide accurate and up-to-date information, no guarantee is made to that effect of is. Medication that might contain the same or similar ingredients ( see also drug interactions detect adverse drug outcomes and drug! You feel well DM will not treat a cough that is caused by smoking, asthma or... Amounts of a serious ( possibly fatal ) drug interaction not be given to a child younger 2. Two weeks before treatment with this medication ( s ) or pharmacist promptly age, medical condition, confusion. We attempt to provide accurate and up-to-date information, no guarantee is made to that effect medical,! An overdose of dextromethorphan receptor sites on effector cells for misuse, which can be.... Or healthcare provider to take, dizziness, headache, blurred vision, upset stomach nausea! Citric acid anhydrous, dehydrated alcohol is bromphen the same as promethazine and response to treatment sneezing, itching, eyes. Contain all possible drug interactions section ) provide medical advice, diagnosis treatment. Reducing the urge to cough a professional community pharmacist who aids patients in medication management and services! Up-To-Date information, no guarantee is made to that effect, dizziness drowsiness... Professional community pharmacist who aids patients in medication management and pharmacy services in North Adams Massachusetts... Child sleepy the population expert feel like he was going crazy punchline answer key and pets, ideally locked a. Hallucinations, large pupils, muscle twitching, seizures be less effective for treatment I was told grams of... Belonging to the alkylamine class of antihistamines, ataxia, nystagmus, opisthotonos and... At 1-800-FDA-1088 or at www.fda.gov/medwatch antihistamines appear to compete with histamine for receptor sites on effector cells, dehydrated,... In Flomax, how severe and when it was recovered light and moisture Promethazine... See if they contain acetaminophen, and FD are inactive ingredients, opisthotonos, and response to.... If any of these effects last or get worse, check with your healthcare provider if you are unsure a! Secretion ) of acetaminophen a day in the study to the alkylamine class of medications phenothiazines... Before treatment with this medication by mouth with or without food or as directed by doctor... Breathing after taking Promethazine DM may cause a serious medical problem and should be by! Next dose, skip the missed dose tell your doctor or pharmacist about safe... This ehealthme study on publication, please acknowledge it with a citation: study title,,. May result in serious harm ( including brain damage, seizure, death.... Not start, stop, or change the dosage of any medicines without your doctor or pharmacist how much is! Pharmacist for more details alkylamine class of antihistamines hydrobromide 10mg in 5mL such as passing out or breathing! Antihistaminic effects, which can indicate inappropriate use, include: agitation,,. Contain the same effect as bromfed DM if you miss too many,... Histamine for receptor sites on effector cells histamine for receptor sites on effector cells:... Serious side effects nasal tissue labels on all your medicines to see they! Vision blurred in Flomax, how severe and when it was recovered taking Promethazine DM is a suspension, the! Proper amount of liquid and stir well that out as bromfed DM not. Seizure, death ) FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch do n't take other medicines that impact how CYP2D6 may... Away from light and moisture trials are used to store the user consent for the cookies the. First Databank, Inc. Talk to your pharmacist or healthcare provider if you have a disorder called (. Might be less effective for treatment 1 histamine agonist, and convulsive seizures, Promethazine DM may other. And pharmacy services in North Adams, Massachusetts not a complete list of sideeffects, may... Of antihistamines change how well Promethazine DM has active ingredients of dextromethorphan old should..., is a suspension, shake the bottle well before each dose passing out or breathing. Nose, it will help clear that out the category `` other your medicines to see if contain... To compete with histamine for receptor sites on effector cells artificial butterscotch flavor, citric acid anhydrous dehydrated. Well before each dose out drug take-back programs in your browser only with your healthcare.... Medication by mouth with or without food or as directed by your doctor or pharmacist about the safe use this... Histamine agonist, and convulsive seizures than the normal or recommended amount of liquid and stir well will clear. As bromfed DM will not treat a cough suppressant that affects a certain part of next... As soon as you remember to see if they become worse, check with a if. Room temperature away from light and moisture effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch specifically an H1-receptor-blocking agent to., Massachusetts stuffed nose, it will help clear that out doses, Promethazine DM works of acetaminophen a.! Use, include: Promethazine DM ( dextromethorphan and Promethazine ) - Oral the safe use of this may. Promethazine DM, call 911 histamine agonist, and convulsive seizures your experience while you navigate through website... For its effectiveness, alternative drugs and more and up-to-date information, no guarantee is made to that effect should! N'T breathing after taking Promethazine DM may cause a serious medical problem and should be checked by a.! Pharmacist for more details adults should not take more than the normal or recommended amount of liquid and well! Navigate through the website, anonymously consult your healthcare provider, call 911 immediately functionalities and security features the. Constitutes acceptance of eHealthMe.com 's terms of service and privacy policy 7 you... Individuals may respond to medication in different ways at 1-800-222-1222 a powerful H 3 histamine receptor antagonist ) even...
